OLIGOMATE® Galacto-oligosaccharides

Yakult's corporate philosophy is to "contribute to the health and happiness of people around the world through the pursuit of excellence in life science in general and our research and experience in microorganisms in particular."In keeping with this philosophy, for more than half a century Yakult has been researching microorganisms that are beneficial to human health, especially the helpful microorganisms that contribute to the health of the gastrointestinal tract.
Specifically, OLIGOMATE promotes the growth of bifidobacteria, a helpful microorganism found in the human intestines. It is also extremely resistant to acid and heating during food processing. We are looking forward to providing your company with OLIGOMATE as an food materesals for your Food for Specified Health Uses and other health-oriented foods.


OLIGOMATE is a galacto-oligosaccharide that contains oligosaccharides found in breast milk(4'galactosyllactose)as the main constituent.
OLIGOMATE promotes the growth of bifidobacteria and lactic acid bacteria, which are the beneficial bacteria in the intestines.
OLIGOMATE is a functional sweetener that contains 55% or more galacto-oligosaccharide and is manufactured by the action of enzymes on lactose.


Characteristics of Galacto-oligosaccharides

1Effect to promote "growth of intestinal bifidobacteria"

Growth of bifidobacteria in the intestines can be promoted by consuming 2.5g per day(*1) of galacto-oligosaccharide.
*1 Approx. 6g per day as OLIGOMATE 55N approx. 4.5g per day as OLIGOMATE 55NP.

2Effect to Improve stools

Increase in bowel movement was obserbed by consuming 5g per day(*2)of galacto-oligosaccharide.
*2 Approx. 12g per day as OLIGOMATE 55N, approx. 9g per day as OLIGOMATE 55NP.


Galactooligosaccharides reach the large intestine without being broken down in the human digestive tract.
Thus, they are sugars that are not easily converted into energy by the body.

4Low cariogenicity (does not easily produce dental cavities)

Galactooligosaccharides cannot be used in the growth of Streptococcus mutans, the bacteria responsible for dental cavities.

Physical properties of OLIGOMATE® 55N


OLIGOMATE 55N has a refined sweet taste, without any characteristic aftertaste.
The degree of sweetness of 32, when sweetness of sucrose is set as 100.

2Heat and acid resistance

OLIGOMATE 55N is stable when heated under acidic conditions and shows extremely high heat stability compared to sucrose.
For there reasons, there is no concern for degradation during the processing of food products.

3Moisture retention effect

OLIGOMATE 55N has excellent moisture retention properties, and the food product maintains the appropriate amout of moisture when OLIGOMATE 55N is added.

4Storage stability

OLIGOMATE 55N remains stable for up to one year when stored at room temperature. It therefore does not require special care for long-term storage or distribution.
*OLIGOMATE 55NP (powder) must be handled carefully, as it easily absorbs moisture.


OLIGOMATE 55N has a browning ability (using the Maillard reaction) that is intermediate to that of sucrose and isomerized sugar. This quality can be used to brown foods nicely.


OLIGOMATE 55N shows a slightly higher viscosity than isomerized sugar.

7Water activity

OLIGOMATE 55N shows a level of water activity close to that of sucrose.


OLIGOMATE 55N shows an osmolarity slightly higher than sucrose.

Specifications Uses Safety

1Specifications of OLIGOMATE®

Description Liquid Powder
Brix sugar content 75.0~76.0 -
Water content - Not more than 3%
Sugar composition
in solid content
Galacto-oligosaccharide Not less than 55% Not less than 55%
Simple sugars and lactose Not more than 45% Not more than 45%
Packaging format 18 L can (NET25kg) Carton (10kg)
Expiration period
1.5 year after manufacture 2 year after manufacture

2Application of OLIGOMATE®

Taking advantage of the characteristics of OLIGOMATE, such as acid resistance, heat resistance, etc., it can be used widely as health-oriented food material.

Dairy Products Fermented milk, lactic acid bacteria beverages, infant formula,
ice cream, and milk beverages Beverages
Beverages Fruit juices, vinegar beverages, coffee beverages, tea beverages,
carbonated soft drinks, tonics and nutrient drinks, alcoholic beverages,
Sweets Candy, cookies, biscuits, snacks, chocolate,
Japanese sweets, and unbaked cake
Dessert Pudding, jelly, Bavarian cream (bavarois), etc.
Frozen dessert Sherbet, ice candy, etc.
Bread Bread, sweet rolls, cooked bread, etc
Jam Jam, marmalade, and other preserved-style products
Others Meat processed products, fish paste products, prepared foods,
tofu honey processed products rice, etc.

3Safety information of OLIGOMATE®

(1)Mutagenicity studies

  1. Reverse mutation test with bacteria : Negative

  2. Micronucleus test with mouse peripheral blood : Negative

  3. Chromosomal aberration test with mammal culture cells : Negative

(2)General toxicity test

  1. 90-day repeated oral toxicity study in rats : NOAEL : 2.0g/kg per day

  2. Results of testing in humans with diarrhea as indicator
    NOAEL(LT) 0.68g/kg
    *Values above are results for OLIGOMATE 55N.

Increasingly expanding possibilities

The Yakult Group achieved the development of industrial application of galactooligosaccharides for the first time anywhere in the world.
They have come to be increasingly used in baby powder milk around the world due to the fact that they are a breast milk-derived ingredient.
Therefore, we deal with various systems necessary for international distribution such as GRAS affirmation*1 in the U.S. for food safety and the EU Novel Food Regulation*2, as well as Kosher*3and HALAL*4.

*1 GRAS Certification
A food certification generally recognized as signifying food safety in the U.S.
*2 Novel Food Regulation
A regulation to examine the safety of foods which are to be distributed in the EU on or after May 15th, 1997.
*3 Kosher Certification
Certification to prove that products are produced according to the codes of Jewish law strictly regulating the ingredients and production processes.
*4 Halal Certification
Certification to prove that products are produced according to the codes of Islamic law strictly regulating the ingredients and production processes.

Product Information