Product Information

OLIGOMATE® ~Bifidobacteria growth-promoting factor~

Yakult's corporate philosophy is to "contribute to the health and happiness of people around the world through the pursuit of excellence in life science in general and our research and experience in microorganisms in particular."In keeping with this philosophy, for more than half a century Yakult has been researching microorganisms that are beneficial to human health, especially the helpful microorganisms that contribute to the health of the gastrointestinal tract.
Specifically, OLIGOMATE® promotes the growth of bifidobacteria, a helpful microorganism found in the human intestines. It is also extremely resistant to acid and heating during food processing. We are looking forward to providing your company with OLIGOMATE® as an food materesals for your Food for Specified Health Uses and other health-oriented foods.


Structure of the main constituent of galacto-oligosaccharide

  • OLIGOMATE® is a galacto-oligosaccharide that contains oligosaccharides found in breast milk(4'galactosyllactose)as the main constituent.

  • OLIGOMATE® promotes the growth of bifidobacteria and lactic acid bacteria, which are the beneficial bacteria in the intestines.

  • OLIGOMATE® is a functional sweetener that contains 55% or more galacto-oligosaccharide and is manufactured by the action of enzymes on lactose.

Characteristics of galactooligosaccharides

Effect to promote "growth of intestinal bifidobacteria"

Improvement of intestinal flora

Growth of bifidobacteria in the intestines can be promoted by consuming 2.5g per day(*1) of galacto-oligosaccharide.

*1 Approx. 6g per day as OLIGOMATE® 55N approx. 4.5g per day as OLIGOMATE® 55NP.

Electron micrograph of bifidobacteria

Effect to Improve stools

Number of weekly bowel movement in subject consuming drink containing 5.0g of galacto-oligosaccharide

Increase in bowel movement was obserbed by consuming 5g per day(*2)of galacto-oligosaccharide.

*2 Approx. 12g per day as OLIGOMATE® 55N, approx. 9g per day as OLIGOMATE® 55NP.


Galactooligosaccharides reach the large intestine without being broken down in the human digestive tract.

Thus, they are sugars that are not easily converted into energy by the body.

Change in the concentration of hydrogen excreted in the breath after oral ingestion of galactooligosaccharides by healthy adults(average for 16 people)

Low cariogenicity (does not easily produce dental cavities)

Galactooligosaccharides cannot be used in the growth of Streptococcus mutans, the bacteria responsible for dental cavities.

Physical properties of OLIGOMATE® 55N


Relative sweetness

OLIGOMATE® 55N has a refined sweet taste, without any characteristic aftertaste.

The degree of sweetness of 32, when sweetness of sucrose is set as 100.

Heat and acid resistance

OLIGOMATE® 55N is stable when heated under acidic conditions and shows extremely high heat stability compared to sucrose.

For there reasons, there is no concern for degradation during the processing of food products.

Heat and acid resistance

Moisture retention effect

OLIGOMATE® 55N has excellent moisture retention properties, and the food product maintains the appropriate amout of moisture when OLIGOMATE® 55N is added.

Moisture retention effect

Storage stability

Storage stability at room temperature (average 23.2℃)

OLIGOMATE® 55N remains stable for up to one year when stored at room temperature. It therefore does not require special care for long-term storage or distribution.

*OLIGOMATE® 55NP (powder) must be handled carefully, as it easily absorbs moisture.


Degree of browning in the presence of amino acids

OLIGOMATE® 55N has a browning ability (using the Maillard reaction) that is intermediate to that of sucrose and isomerized sugar. This quality can be used to brown foods nicely.


Viscosity change with temperature

OLIGOMATE® 55N shows a slightly higher viscosity than isomerized sugar.

Water activity

Change in water activity with sugar concentration

OLIGOMATE® 55N shows a level of water activity close to that of sucrose.


Osmolarity of various sugars

OLIGOMATE® 55N shows an osmolarity slightly higher than sucrose.

Specifications Uses Safety

Specifications of OLIGOMATE®

Description Liquid Powder
Brix sugar content 75.0~76.0 -
Water content - Not more than 3%
Sugar composition
in solid content
Galacto-oligosaccharide Not less than 55% Not less than 55%
Simple sugars and lactose Not more than 45% Not more than 45%
Packaging format 18 L can (NET25kg) Carton (10kg)
Expiration period
One year after manufacture Two year after manufacture

Application of OLIGOMATE®

Taking advantage of the characteristics of OLIGOMATE®, such as acid resistance, heat resistance, etc., it can be used widely as health-oriented food material.

Dairy Products Fermented milk, lactic acid bacteria beverages, infant formula,
ice cream, and milk beverages Beverages
Beverages Fruit juices, vinegar beverages, coffee beverages, tea beverages,
carbonated soft drinks, tonics and nutrient drinks, alcoholic beverages,
Sweets Candy, cookies, biscuits, snacks, chocolate,
Japanese sweets, and unbaked cake
Dessert Pudding, jelly, Bavarian cream (bavarois), etc.
Frozen dessert Sherbet, ice candy, etc.
Bread Bread, sweet rolls, cooked bread, etc
Jam Jam, marmalade, and other preserved-style products
Others Meat processed products, fish paste products, prepared foods,
tofu honey processed products rice, etc.

Safety information of OLIGOMATE®

(1)Mutagenicity studies
①Reverse mutation test with bacteria : Negative
②Micronucleus test with mouse peripheral blood : Negative
③Chromosomal aberration test with mammal culture cells : Negative
(2)General toxicity test
①90-day repeated oral toxicity study in rats : NOAEL : 2.0g/kg per day
②Results of testing in humans with diarrhea as indicator
  • NOAEL(LT) 0.68g/kg

*Values above are results for OLIGOMATE® 55N.

Increasingly expanding possibilities

The Yakult Group achieved the development of industrial application of galactooligosaccharides for the first time anywhere in the world.
They have come to be increasingly used in baby powder milk around the world due to the fact that they are a breast milk-derived ingredient.
Therefore, we deal with various systems necessary for international distribution such as GRAS affirmation*1 in the U.S. for food safety and the EU Novel Food Regulation*2, as well as Kosher*3and HALAL*4.

*1 GRAS Certification

A food certification generally recognized as signifying food safety in the U.S.

*2 Novel Food Regulation
A regulation to examine the safety of foods which are to be distributed in the EU on or after May 15th, 1997.
*3 Kosher Certification
Certification to prove that products are produced according to the codes of Jewish law strictly regulating the ingredients and production processes.
*4 Halal Certification
Certification to prove that products are produced according to the codes of Islamic law strictly regulating the ingredients and production processes.

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